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Unusual Deposits in the Superficial Corneal Stroma Following Combined Use of Topical Corticosteroid and Beta-blocking Medication by W. M. M. Huige; W. H. Beekhuis; W. J. Rijneveld; N. Schrage; L. Remeijer is a Medicine article available to read on EtoBox.

What is Unusual Deposits in the Superficial Corneal Stroma Following Combined Use of Topical Corticosteroid and Beta-blocking Medication about?

Clinical observation of eight patients with superficial stromal precipitation of calcium phosphate is presented. In all cases the predisposing factors for the formation of these depositions were: epithelial defects and the combined use of topical dexamethason phosphate or prednisolon phosphate with topical beta-blocking agents. In two patients the medication that gave rise to these precipitates was used without preservatives, suggesting that the medication itself and not the preservatives contribute to the deposits. Discontinuance of simultaneous administration of the steroids and beta-blocking agents prevented further formation of precipitates. The authors suggest an interaction between simultaneously given steroid and betablocking agents, giving rise to calcium phosphate precipitates when an epithelial defect is present which allows easy access to the superficial corneal stroma.

Who reads Unusual Deposits in the Superficial Corneal Stroma Following Combined Use of Topical Corticosteroid and Beta-blocking Medication?

Author

W. M. M. Huige; W. H. Beekhuis; W. J. Rijneveld; N. Schrage; L. Remeijer

Publisher

Springer-Verlag; Kluwer Academic Publishers; Springer Science and Business Media LLC (ISSN 0012-4486)

Published

1990

Language

EN

Field

Medicine (Health Sciences)