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Evaluation of Different Doses of Propofol in Xylazine Pre-medicated Horses by Adriana FG Frias; Firmino Mársico; Ignacio A Gómez de Segura; Paulo RL Nascimento Jr; Amary Nascimento; Joao HN Soares; Nadia R Almosny is a Veterinary article available to read on EtoBox.

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## Objective: To characterize responses to different doses of propofol in horses pre-medicated with xylazine. ## Animals: Six adult horses (five females and one male). ## Methods: Each horse was anaesthetized four times with either ketamine or propofol in random order at 1-week intervals. horses were pre-medicated with xylazine (1.1 mg kg-1 iv over a minute), and 5 minutes later anaesthesia was induced with either ketamine (2.2 mg kg-1 iv) or propofol (1, 2 and 4 mg kg-1 iv; low, medium and high doses, respectively). data were collected continuously (electrocardiogram) or after xylazine administration and at 5, 10 and 15 minutes after anaesthetic induction (arterial pressure, respiratory rate, ph, pao2, paco2 and o2 saturation). anaesthetic induction and recovery were qualitatively and quantitatively assessed. ## Results: Differences in the quality of anaesthesia were observed; the low dose of propofol resulted in a poorer anaesthetic induction that was insufficient to allow intubation, whereas the high dose produced an excellent quality of induction, free of excitement. recorded anaesthesia times were similar between propofol at 2 mg kg-1 and ketamine with prolonged and shorter re

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Author

Adriana FG Frias; Firmino Mársico; Ignacio A Gómez de Segura; Paulo RL Nascimento Jr; Amary Nascimento; Joao HN Soares; Nadia R Almosny

Publisher

John Wiley and Sons; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 1467-2987)

Published

2003

Language

EN

Field

Veterinary (Health Sciences)