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Can I read Leu-7 Immunoreactivity in Human and Rat Embryonic Hearts, with Special Reference to the Development of the Conduction Tissue on EtoBox?
Leu-7 Immunoreactivity in Human and Rat Embryonic Hearts, with Special Reference to the Development of the Conduction Tissue by Takayoshi Ikeda; Keisuke Iwasaki; Isao Shimokawa; Hidetaka Sakai; Hajime Ito; Takeshi Matsuo is a Neuroscience article available to read on EtoBox.
What is Leu-7 Immunoreactivity in Human and Rat Embryonic Hearts, with Special Reference to the Development of the Conduction Tissue about?
The distribution pattern of Leu-7 (HNK-1) in developing human embryonic hearts and rat hearts was studied by immunohistochemistry. Human and rat embryos at Streeter's stages XIII approximately XX and fetus stage I were used. Leu-7, which is absent in the newborn rat heart, is expressed transiently in the embryo and fetus I stages. The earliest embryonic heart shows two incomplete circular structures with immunoreactivity in the myocardium along the primitive atrioventricular cushion and bulboventricular canal. These two structures become localized topographically in the definitive atrioventricular node and atrioventricular bundle after rearrangement and partial disappearance during embryonic development. At Streeter's stages XVIII approximately XX, Leu-7 immunoreactivity appears to localize topographically in almost all the pathways of the conduction system, although some discontinuities are observed in the atrioventricular junction and atrial internodal tracts. Thereafter, immunoreactivity decreases gradually and differentially by site and stage. The precise nature of Leu-7 immunoreactive cells, that is, whether or not they are neurogenic or myogenic, is not revealed by this study
Who reads Leu-7 Immunoreactivity in Human and Rat Embryonic Hearts, with Special Reference to the Development of the Conduction Tissue?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Takayoshi Ikeda; Keisuke Iwasaki; Isao Shimokawa; Hidetaka Sakai; Hajime Ito; Takeshi Matsuo
- Publisher
- Springer; Springer-Verlag; Springer Verlag; J.F. Bergmann; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 0340-2061)
- Published
- 1990
- Language
- EN
- Field
- Neuroscience (Life Sciences)