Opening book details…
Can I read Hydrophilic electrospun polyurethane nanofiber matrices for hMSC culture in a microfluidic cell chip on EtoBox?
Hydrophilic electrospun polyurethane nanofiber matrices for hMSC culture in a microfluidic cell chip by Kwang Ho Lee; Gu Han Kwon; Su Jung Shin; Ju‐Yeoul Baek; Dong Keun Han; Yongdoo Park; Sang Hoon Lee is a Engineering article available to read on EtoBox.
What is Hydrophilic electrospun polyurethane nanofiber matrices for hMSC culture in a microfluidic cell chip about?
## Abstract Mimicking cellular microenvironments by MEMS technology is one of the emerging research areas. Integrated biomimetic systems with nanofiber polymer networks and microfluidic chips were fabricated and cellular behaviors were observed by changing surface characteristics of nanofibers and flow rates of microchannels. Modification of polyurethane nanofiber surfaces were achieved by grafting acrylic acid with plasma treatment and these nanofiber matrices were employed in a poly(dimethylsiloxane) based microfluidic chip. The surface characteristics of both electrospun nanofiber matrices was evaluated by measuring contact angle, porosity, and chemical structure using attenuated total reflection‐Fourier transform infrared spectrometry. After modification, a terminal carboxyl group formed on the nanofiber surface and the wettability increased significantly. Human MSCs were seeded on the nanofiber matrices and a morphological investigation with actin filament staining and scanning electron microscopy was performed. A proliferation test by WST‐1 and Live/Dead assay were performed to investigate the cell culture environment. It was observed that the cells on the AA‐grafted nanofibe
Who reads Hydrophilic electrospun polyurethane nanofiber matrices for hMSC culture in a microfluidic cell chip?
It is typically read by researchers, students, and practitioners in Engineering.
- Author
- Kwang Ho Lee; Gu Han Kwon; Su Jung Shin; Ju‐Yeoul Baek; Dong Keun Han; Yongdoo Park; Sang Hoon Lee
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1549-3296)
- Published
- 2008
- Language
- EN
- Field
- Engineering (Physical Sciences)