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Statistical implications of utility weighted and equally weighted HRQL measures: an empirical study by Caitlyn T. Wilke; A. Simon Pickard; Surrey M. Walton; Joern Moock; Thomas Kohlmann; Todd A. Lee is a Economics, Econometrics and Finance article available to read on EtoBox.

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## Abstract The utility‐based approach to health measurement, exemplified by EQ‐5D and Health Utilities Index (HUI), has been challenged on a theoretical basis, but the statistical implications of such an approach have received little attention. To empirically investigate this issue, psychometric properties and statistical efficiency of the EQ‐5D and HUI Mark 3 (HUI3) classifiers were compared when scored using preference weighted (WPS) and equally weighted summary scores using two longitudinal datasets (__n__~stroke~=124; __n__~rehabilitation~=264). Test–retest reliability, construct validity, responsiveness, and relative efficiency (RE) ratios (with bootstrapped 95% confidence intervals) were examined. WPS had slightly lower test–retest reliability, particularly for EQ‐5D (intraclass correlation coefficient=0.61 vs 0.72). For known‐groups comparisons, WPS had greater inferential power for both EQ‐5D and HUI3 (RE>1). No significant differences in sensitivity to change were observed for EQ‐5D [0.71 (95% CI: 0.29,1.33)≤RE≤0.96(95% CI: 0.69,1.32)] or HUI3 [0.97 (95% CI: 0.89,1.03)≤RE≤1.23 (95% CI: 0.98,1.72)]. Implications of weighted scoring will depend on whether the weights are gr

Who reads Statistical implications of utility weighted and equally weighted HRQL measures: an empirical study?

Author

Caitlyn T. Wilke; A. Simon Pickard; Surrey M. Walton; Joern Moock; Thomas Kohlmann; Todd A. Lee

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1057-9230)

Published

2009

Language

EN

Field

Economics, Econometrics and Finance (Social Sciences)