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Restrictive Annuloplasty or Replacement on Reverse Remodeling for Nonischemic Dilated Cardiomyopathy by Yusuke Misumi; Masashi Kawamura; Daisuke Yoshioka; Takuji Kawamura; Ai Kawamura; Yoshito Ito; Tsubasa Mikami; Masaki Taira; Kazuo Shimamura; Shigeru Miyagawa; Osaka Cardiovascular Surgery Research (OSCAR) study group is a Medicine article available to read on EtoBox.
What is Restrictive Annuloplasty or Replacement on Reverse Remodeling for Nonischemic Dilated Cardiomyopathy about?
## Background For patients with nonischemic dilated cardiomyopathy (NIDCM), the indications for and results of mitral surgery remain controversial. We reviewed a strategy of mitral repair and replacement for clinically relevant secondary mitral regurgitation (MR) in patients with NIDCM. ## Methods We retrospectively reviewed 65 patients with advanced NIDCM (LVEF < 40%) who underwent mitral surgery. Of them, 47 (72%) underwent mitral annuloplasty and 18 (28%) replacement for secondary MR. The primary endpoint was postoperative reduction in indexed LV end-systolic volume (LVESVI). ## Results At baseline, there was no intergroup difference in LVESVI (123 ± 47 vs. 147 ± 37 ml/m^2^, __P__ = 0.055), LVEF (27 ± 8% vs. 25 ± 6%, __P__ = 0.41), incidence of severe MR (57% (27/47) vs. 72% (13/18), __P__ = 0.40), or EuroSCORE II score (6.2% vs. 7.6%, __P__ = 0.90). At 6 months, the annuloplasty group reduced LVESVI to a greater degree than the replacement group (__P__ < 0.001), yielding significantly smaller postoperative LVESVI (96 ± 59 vs. 154 ± 61 ml/m^2^, __P__ < 0.001) and better LVEF (__P__ < 0.001). The rates of moderate/severe recurrent MR were 17% (8/47) and 0%, respectively. Multivar
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- Author
- Yusuke Misumi; Masashi Kawamura; Daisuke Yoshioka; Takuji Kawamura; Ai Kawamura; Yoshito Ito; Tsubasa Mikami; Masaki Taira; Kazuo Shimamura; Shigeru Miyagawa; Osaka Cardiovascular Surgery Research (OSCAR) study group
- Publisher
- BioMed Central
- Published
- 2024
- Language
- EN
- Field
- Medicine (Health Sciences)