Can I read Language Network Lateralization Is Reflected Throughout the Macroscale Functional Organization of Cortex on EtoBox?

Language Network Lateralization Is Reflected Throughout the Macroscale Functional Organization of Cortex by Loïc Labache; Tian Ge; B. T. Thomas Yeo; Avram J. Holmes is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Language Network Lateralization Is Reflected Throughout the Macroscale Functional Organization of Cortex about?

Hemispheric specialization is a fundamental feature of human brain organization. However, it is not yet clear to what extent the lateralization of specific cognitive processes may be evident throughout the broad functional architecture of cortex. While the majority of people exhibit left-hemispheric language dominance, a substantial minority of the population shows reverse lateralization. Using twin and family data from the Human Connectome Project, we provide evidence that atypical language dominance is associated with global shifts in cortical organization. Individuals with atypical language organization exhibit corresponding hemispheric differences in the macroscale functional gradients that situate discrete large-scale networks along a continuous spectrum, extending from unimodal through association territories. Analyses reveal that both language lateralization and gradient asymmetries are, in part, driven by genetic factors. These findings pave the way for a deeper understanding of the origins and relationships linking population-level variability in hemispheric specialization and global properties of cortical organization.

Who reads Language Network Lateralization Is Reflected Throughout the Macroscale Functional Organization of Cortex?

Author

Loïc Labache; Tian Ge; B. T. Thomas Yeo; Avram J. Holmes

Publisher

Springer Science and Business Media LLC

Published

2023

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)