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Can I read Craniocervical instability in patients with Ehlers-Danlos syndrome: controversies in diagnosis and management on EtoBox?
Craniocervical instability in patients with Ehlers-Danlos syndrome: controversies in diagnosis and management by Gordon Mao; Srujan Kopparapu; Yike Jin; A. Daniel Davidar; Andrew M. Hersh; Carly Weber-Levine; Nicholas Theodore is a Medicine article available to read on EtoBox.
What is Craniocervical instability in patients with Ehlers-Danlos syndrome: controversies in diagnosis and management about?
Ehlers-Danlos syndrome (EDS) is a rare hereditary condition that can result in ligamentous laxity and hypermobility of the cervical spine. A subset of patients can develop clinical instability of the craniocervical junction associated with pain and neurological dysfunction, potentially warranting treatment with occipitocervical fixation (OCF). Surgical decision-making in patients with EDS can be complicated by difficulty distinguishing from hypermobility inherent in the disease and true pathological instability necessitating intervention. Here we comprehensively review the available medical literature to critically appraise the evidence behind various proposed definitions of instability in the EDS population, and summarize the available outcomes data after OCF. Several radiographic parameters have been used, including the clivo-axial angle, basion-axial interval, and pB-C2 measurement. Despite increasing recognition of EDS by spine surgeons, there remains a paucity of data supporting proposed radiographic parameters for spinal instability among EDS patients. Furthermore, there is a lack of high-quality evidence concerning the efficacy of surgical treatments for chronic debilitating
Who reads Craniocervical instability in patients with Ehlers-Danlos syndrome: controversies in diagnosis and management?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Gordon Mao; Srujan Kopparapu; Yike Jin; A. Daniel Davidar; Andrew M. Hersh; Carly Weber-Levine; Nicholas Theodore
- Publisher
- Elsevier BV
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)