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Valid μ Finite Element Models of Vertebral Trabecular Bone Can Be Obtained Using Tissue Properties Measured with Nanoindentation Under Wet Conditions by Uwe Wolfram; Hans-Joachim Wilke; Philippe K. Zysset is a Medicine article available to read on EtoBox.

What is Valid μ Finite Element Models of Vertebral Trabecular Bone Can Be Obtained Using Tissue Properties Measured with Nanoindentation Under Wet Conditions about?

Osteoporosis-related vertebral fractures represent a major public health problem. Anatomy-specific CT-based finite element (FE) simulations could help in identifying which vertebrae have the highest risk of fracture and thus help to decide upon the need for vertebroplasty or other surgical intervention. Continuum level FE simulations require effective macroscopic material properties of the vertebra. Micro finite element (mFE) models can be used to circumvent the difficult experiments that are necessary to determine these effective properties. From a quantitative point of view, these mFE models depend critically on the chosen trabecular tissue properties. The question remains whether linear elastic mFE models of vertebral trabecular bone with and without specimen-specific tissue properties yield similar results as non-destructive macroscopic experiments under moist conditions. mFE models were set up from mCT scans with specimen-specific or average tissue moduli measured by nanoindentation under dry and wet testing conditions. Non-destructive macroscopic mechanical compression, tension and torsion tests were performed. Experimentally obtained and simulated apparent stiffnesses were c

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Author

Uwe Wolfram; Hans-Joachim Wilke; Philippe K. Zysset

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0021-9290)

Published

2010

Language

EN

Field

Medicine (Health Sciences)