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Long-COVID in Scotland Study: a nationwide, population cohort study by Jill Pell; Claire Hastie; David Lowe; Andrew McAuley; Andrew Winter; Nicholas Mills; Corri Black; Janet Scott; Catherine O'Donnell; David Blane; Susan Browne; Tracy Ibbotson is a scholarly article available to read on EtoBox.

What is Long-COVID in Scotland Study: a nationwide, population cohort study about?

## Abstract BACKGROUNDWith increasing numbers of people infected with SARS-CoV-2, a better understanding of long-COVID is required to inform health and social care support.METHODSA nationwide, ambidirectional, population cohort was constructed of adults in Scotland with a positive SARS-CoV-2 PCR test from April 2020 to May 2021 and a matched, never infected comparison group. Recovery status, symptoms, quality of life, impaired daily activities, hospitalization and death were ascertained via repeated self-completed questionnaires, at 6, 12 and 18-months follow-up, and linkage to hospitalization and death records.RESULTSThe cohort comprised 31,486 symptomatic and 1,795 asymptomatic infected individuals, and 62,957 never infected individuals. Of the former, 1,856 (6%) had not recovered and 13,350 (42%) only partially. Lack of recovery was associated with severe (hospitalized) infection, older age, female sex, deprivation, respiratory disease, depression and multimorbidity. Twenty-four persistent symptoms were independently associated with previous infection including breathlessness (OR 3.44, 95% CI 3.29–3.59), palpitations (OR 2.51, OR 2.37–2.67), chest pain (OR 2.10, 95% CI 1.97–2.24

Author

Jill Pell; Claire Hastie; David Lowe; Andrew McAuley; Andrew Winter; Nicholas Mills; Corri Black; Janet Scott; Catherine O'Donnell; David Blane; Susan Browne; Tracy Ibbotson

Publisher

Research Square Platform LLC

Published

2022

Language

EN