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Next-Gen Sequencing in Infectious Disease by Laurine Pigosso is a document available to read on EtoBox.

What is Next-Gen Sequencing in Infectious Disease about?

This article discusses how next generation sequencing is revolutionizing the diagnosis of infectious diseases by allowing for whole genome sequencing directly from clinical samples without needing to culture pathogens first. This avoids limitations of targeted PCR tests and allows detection of both known and unknown pathogens. Challenges include increasing the ratio of microbial to host nucleic acids in samples and obtaining sufficient coverage to determine antibiotic resistance or virulence factors from pa

Author

Laurine Pigosso

Language

EN