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Increase in methicillin-susceptible Staphylococcus aureus bloodstream infections in Switzerland: a nationwide surveillance study (2008–2021) by Luzia Renggli; Michael Gasser; Niccolò Buetti; Andreas Kronenberg; the Swiss Centre for Antibiotic Resistance is a Medicine article available to read on EtoBox.

What is Increase in methicillin-susceptible Staphylococcus aureus bloodstream infections in Switzerland: a nationwide surveillance study (2008–2021) about?

## Purpose An increasing burden of __Staphylococcus aureus__ bloodstream infections (BSI), despite a decrease in the percentage of methicillin-resistant __S. aureus__ (MRSA), was described recently in other European countries. The main aim of this study was to analyse recent temporal trends of __S. aureus__, methicillin-susceptible __S. aureus__ (MSSA) and MRSA BSI for Switzerland as well as the different linguistic regions within Switzerland. An additional aim was to estimate potential differences among patient-based and epidemiological risk factors. ## Methods A retrospective observational study was conducted in Switzerland over a period of 14 years (2008–2021)__.__ Trends in __S. aureus__, MSSA and MRSA BSI were analysed by applying linear regression models. ## Results __Staphylococcus aureus__ BSI increased by + 30% from 19.7 to 25.6 cases per 100,000 inhabitants between 2008 and 2021 (__P__ < 0.01) in Switzerland. Thereof, MSSA increased by + 37% from 17.8 to 24.4 cases per 100,000 inhabitants (__P__ < 0.01). MRSA decreased from 1.9 to 1.2 cases per 100,000 inhabitants (__P__ < 0.01), which was driven by decreasing incidence in the French-speaking region. MSSA BSI increased si

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Author
Luzia Renggli; Michael Gasser; Niccolò Buetti; Andreas Kronenberg; the Swiss Centre for Antibiotic Resistance
Publisher
Springer Science and Business Media LLC
Published
2023
Language
EN
Field
Medicine (Health Sciences)

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