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Structural and Functional Energetic Linkages in Allosteric Regulation of Muscle Pyruvate Kinase by Lee, J. Ching is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Structural and Functional Energetic Linkages in Allosteric Regulation of Muscle Pyruvate Kinase about?

<p>In the past several years, there has been an explosion in the ability of biologists, molecular biologists and biochemists to collect vast amounts of data on their systems. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions. The use of thermodynamics in biological research is used as an “energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. These methods look to answer: What are the sources of energy that drive the function? Which of the pathways are of biological significance? </p> <p>As the base of macromolecular structures continues to expand through powerful techniques of molecular biology, such as X-ray crystal data and spectroscopy methods, the importance of tested and reliable methods for answering these questions will continue to expand as well.</p><br><br><p>* Elucidates the relationships between structure and energetics and their applications to molecular design, aiding researchers in the design of medically important molecules * Provides a "must-have" methods volum

Who reads Structural and Functional Energetic Linkages in Allosteric Regulation of Muscle Pyruvate Kinase?

Author

Lee, J. Ching

Publisher

Elsevier/Academic Press

Published

2011

Language

EN

ISBN

9780123812681

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)