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Catalyst-free, Solvent-promoted and Scalable Multicomponent Synthesis of 3-Aminoalkylated Indoles via a Mannich-type Reaction by Jian-Fei Cao; Yan-Li Chen; Zhi Guan; Yan-Hong He is a Chemistry article available to read on EtoBox.
What is Catalyst-free, Solvent-promoted and Scalable Multicomponent Synthesis of 3-Aminoalkylated Indoles via a Mannich-type Reaction about?
A catalyst-free, solvent-promoted and scalable three-component Mannich-type reaction of indoles, aromatic aldehydes and secondary amines for the synthesis of 3-(1-dialkylaminoalkyl)-1H-indoles has been developed. The protocol provided a mild, simple and highly atom-economic alternative to prepare the title compounds, and the corresponding products could be obtained in good to excellent yields in most cases.
Who reads Catalyst-free, Solvent-promoted and Scalable Multicomponent Synthesis of 3-Aminoalkylated Indoles via a Mannich-type Reaction?
It is typically read by researchers, students, and practitioners in Chemistry.
- Author
- Jian-Fei Cao; Yan-Li Chen; Zhi Guan; Yan-Hong He
- Publisher
- Walter de Gruyter GmbH
- Published
- 2014
- Language
- EN
- Field
- Chemistry (Physical Sciences)
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