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Study on Cellular Adhesion of Human Osteoblasts on Nano‐structured Diamond Films by Marie Kalbacova; Antonin Broz; Oleg Babchenko; Alexander Kromka is a Physics and Astronomy article available to read on EtoBox.

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## Abstract The need of new biocompatible materials with superior properties and flexibility in their surface termination and functionalization for medical applications is constantly increasing. Due to the combination of intrinsic properties, chemically deposited diamond thin films are proposed as one of the most promising material in this field. They are chemically/mechanically/physically stable and their surface can be modified by a variety of chemical or plasmatic techniques. In the present work, different diamond nano‐structures, i.e. nano‐rods, ultra nano‐cones and nano‐cones, were prepared by plasma etching process by applying various masking materials (Ni, Au and diamond powder). The impact of these diamond nano‐structures on the growth of human osteoblasts was investigated by fluorescence microscopy. We observed that adhesion of osteoblasts varied, depending upon the diamond nano‐structure as visualized, 1 or 48 h after seeding. Many but very fine focal adhesions are formed on nano‐rods; however, few but large ones are formed on ultra nano‐cones and nano‐cones. The cell adhesion was controlled by the nano‐structuring, thereupon their usage in bio‐medical applications is con

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Author

Marie Kalbacova; Antonin Broz; Oleg Babchenko; Alexander Kromka

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Ltd.; Wiley (ISSN 0370-1972)

Published

2009

Language

EN

Field

Physics and Astronomy (Physical Sciences)