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Pharmaceutical significance of cellulose: A review by S. Kamel; N. Ali; K. Jahangir; S. M. Shah; A. A. El-Gendy is a Materials Science article available to read on EtoBox.

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The amalgamation of polymer and pharmaceutical sciences led to the introduction of polymer in the design and development of drug delivery systems. Polymeric delivery systems are mainly intended to achieve controlled or sustained drug delivery. Polysaccharides fabricated into hydrophilic matrices remain popular biomaterials for controlled-release dosage forms and the most abundant naturally occurring biopolymer is cellulose; so hdroxypropylmethyl cellulose, hydroxypropyl cellulose, microcrystalline cellulose and hydroxyethyl cellulose can be used for production of time controlled delivery systems. Additionally microcrystalline cellulose, sodium carboxymethyl cellulose, hydroxypropylmethyl cellulose, hydroxyethyl cellulose as well as hydroxypropyl cellulose are used to coat tablets. Cellulose acetate phthalate and hydroxymethyl cellulose phthalate are also used for enteric coating of tablets. Targeting of drugs to the colon following oral administration has also been accomplished by using polysaccharides such as hdroxypropylmethyl cellulose and hydroxypropyl cellulose in hydrated form; also they act as binders that swell when hydrated by gastric media and delay absorption. This paper

Who reads Pharmaceutical significance of cellulose: A review?

Author

S. Kamel; N. Ali; K. Jahangir; S. M. Shah; A. A. El-Gendy

Publisher

Department of Polymer Engineering, Scientific Society of Mechanical Engineering

Published

2008

Language

EN

Field

Materials Science (Physical Sciences)