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Arborization pattern of Engrailed-positive neural lineages reveal neuromere boundaries in the Drosophila brain neuropil by Abhilasha Kumar; S. Fung; Robert Lichtneckert; Heinrich Reichert; Volker Hartenstein is a Neuroscience article available to read on EtoBox.
What is Arborization pattern of Engrailed-positive neural lineages reveal neuromere boundaries in the Drosophila brain neuropil about?
## Abstract The __Drosophila__ brain is a highly complex structure composed of thousands of neurons that are interconnected in numerous exquisitely organized neuropil structures such as the mushroom bodies, central complex, antennal lobes, and other specialized neuropils. While the neurons of the insect brain are known to derive in a lineage‐specific fashion from a stereotyped set of segmentally organized neuroblasts, the developmental origin and neuromeric organization of the neuropil formed by these neurons is still unclear. In this study we used genetic labeling techniques to characterize the neuropil innervation pattern of __engrailed__‐expressing brain lineages of known neuromeric origin. We show that the neurons of these lineages project to and form most arborizations, in particular all of their proximal branches, in the same brain neuropil compartments in embryonic, larval and adult stages. Moreover, we show that __engrailed__‐positive neurons of differing neuromeric origin respect boundaries between neuromere‐specific compartments in the brain. This is confirmed by an analysis of the arborization pattern of __empty spiracles__‐expressing lineages. These findings indicate th
Who reads Arborization pattern of Engrailed-positive neural lineages reveal neuromere boundaries in the Drosophila brain neuropil?
It is typically read by researchers, students, and practitioners in Neuroscience.
- Author
- Abhilasha Kumar; S. Fung; Robert Lichtneckert; Heinrich Reichert; Volker Hartenstein
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley; Research Square (ISSN 0021-9967)
- Published
- 2009
- Language
- EN
- Field
- Neuroscience (Life Sciences)