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Can I read Regulation of Renal Tubular Secretion of Organic Compounds on EtoBox?
Regulation of Renal Tubular Secretion of Organic Compounds by Berkhin, Efim B.; Humphreys, Michael H. is a Medicine article available to read on EtoBox.
What is Regulation of Renal Tubular Secretion of Organic Compounds about?
## Background: Information on the molecular basis underlying organic anion and cation transport in renal tubules has expanded in recent years with the identification and characterization of numerous transporters. however, little is known about the regulation of this transport. ## Methods: Both english and russian language studies dealing with the regulation of organic ion transport by the kidney have been reviewed. ## Results: This review summarizes the literature on the physiological and pharmacological aspects of the regulation of organic ion transport, linking this information where possible to underlying transport mechanisms. current models of the tubular secretion of organic anions and cations are reviewed. factors that inhibit or enhance tubular secretion of xenobiotics are described, and their influence on proximal tubule cell transport and function is discussed. important roles for substrate stimulation, the adrenergic nervous system, numerous hormones, p-glycoprotein, and protein kinase c activity have been identified. ## Conclusions: Despite considerable advances in the understanding of basic transport pathways and mechanisms involved in the tubular secretion of organic c
Who reads Regulation of Renal Tubular Secretion of Organic Compounds?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Berkhin, Efim B.; Humphreys, Michael H.
- Publisher
- Nature Publishing Group; Elsevier ; Elsevier Inc.; Elsevier BV; ScienceOpen (ISSN 0085-2538)
- Published
- 2001
- Language
- EN
- Field
- Medicine (Health Sciences)