Opening book details…
Can I read Correlations between fMRI activation and individual psychotic symptoms in un-medicated subjects at high genetic risk of schizophrenia on EtoBox?
Correlations between fMRI activation and individual psychotic symptoms in un-medicated subjects at high genetic risk of schizophrenia by Heather C Whalley; Viktoria-Eleni Gountouna; Jeremy Hall; Andrew McIntosh; Marie-Claire Whyte; Enrico Simonotto; Dominic E Job; David GC Owens; Eve C Johnstone; Stephen M Lawrie is a Psychology article available to read on EtoBox.
What is Correlations between fMRI activation and individual psychotic symptoms in un-medicated subjects at high genetic risk of schizophrenia about?
## Background: It has been proposed that different types of psychopathology in schizophrenia may reflect distinguishable pathological processes. In the current study we aimed to address such associations in the absence of confounders such as medication and disease chronicity by examining specific relationships between fMRI activation and individual symptom severity scores in un-medicated subjects at high genetic risk of schizophrenia. ## Methods: Associations were examined across two functional imaging paradigms: the Hayling sentence completion task, and an encoding/retrieval task, comprising encoding (at word classification) and retrieval (old word/new word judgement). Symptom severity was assessed using the positive and negative syndrome scale (PANSS). Items examined were hallucinations, delusions, and suspiciousness/persecution. ## Results: Associations were seen in the anterior middle temporal gyrus in relation to hallucination scores during the sentence completion task, and in the medial temporal lobe in association with suspiciousness/persecution scores in the encoding/retrieval task. Cerebellar activation was associated with delusions and suspiciousness/persecution scores ac
Who reads Correlations between fMRI activation and individual psychotic symptoms in un-medicated subjects at high genetic risk of schizophrenia?
It is typically read by researchers, students, and practitioners in Psychology.
- Author
- Heather C Whalley; Viktoria-Eleni Gountouna; Jeremy Hall; Andrew McIntosh; Marie-Claire Whyte; Enrico Simonotto; Dominic E Job; David GC Owens; Eve C Johnstone; Stephen M Lawrie
- Publisher
- BioMed Central; Springer (Biomed Central Ltd.); London: BioMed Central, 2001-; Springer Science and Business Media LLC; Society for Mining, Metallurgy and Exploration Inc. (ISSN 1471-244X)
- Published
- 2007
- Language
- EN
- Field
- Psychology (Social Sciences)