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Clinical characteristics and outcome of critically ill COVID-19 patients with acute kidney injury: a single centre cohort study by On behalf of the University Hospital Southampton Critical Care Team and the REACT COVID investigators (author);Lowe, R. (author);Ferrari, M. (author);Nasim-Mohi, M. (author);Jackson, A. (author);Beecham, R. (author);Veighey, K. (author);Cusack, R. (author);Richardson, D. (author);Grocott, MPW (author);Levett, DZH (author);Dushianthan, A. (author) is a Medicine article available to read on EtoBox.
What is Clinical characteristics and outcome of critically ill COVID-19 patients with acute kidney injury: a single centre cohort study about?
## Abstract ## Background Acute kidney injury (AKI) is a common manifestation among patients critically ill with SARS-CoV-2 infection (Coronavirus 2019) and is associated with significant morbidity and mortality. The pathophysiology of renal failure in this context is not fully understood, but likely to be multifactorial. The intensive care unit outcomes of patients following COVID-19 acute critical illness with associated AKI have not been fully explored. We conducted a cohort study to investigate the risk factors for acute kidney injury in patients admitted to and intensive care unit with COVID-19, its incidence and associated outcomes. ## Methods We reviewed the medical records of all patients admitted to our adult intensive care unit suffering from SARS-CoV-2 infection from 14th March 2020 until 12th May 2020. Acute kidney injury was defined using the Kidney Disease Improving Global Outcome (KDIGO) criteria. The outcome analysis was assessed up to date as 3rd of September 2020. ## Results A total of 81 patients admitted during this period. All patients had acute hypoxic respiratory failure and needed either noninvasive or invasive mechanical ventilatory support. Thirty-six pati
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- Author
- On behalf of the University Hospital Southampton Critical Care Team and the REACT COVID investigators (author);Lowe, R. (author);Ferrari, M. (author);Nasim-Mohi, M. (author);Jackson, A. (author);Beecham, R. (author);Veighey, K. (author);Cusack, R. (author);Richardson, D. (author);Grocott, MPW (author);Levett, DZH (author);Dushianthan, A. (author)
- Publisher
- Springer Science and Business Media LLC
- Published
- 2021
- Language
- EN
- Field
- Medicine (Health Sciences)