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Symptoms of Primary Hyperparathyroidism in Men and Women: The Same but Different? by Weber, Theresia; Hillenbrand, Andreas; Peth, Simon; Hummel, Rainer is a Medicine article available to read on EtoBox.

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**__Introduction and Objective:__** Typical symptoms for primary hyperparathyroidism (pHPT) include osteoporosis, bone or joint pain, and nephrolithiasis, as well as fatigue, depression, gastritis, and cardiovascular disease. The female:male ratio was 3:1. The aim of this retrospective study was to evaluate the possible influence of gender-specific aspects of these symptoms. **__Methods:__** From February 2018 to November 2019, parathyroid surgery was performed in 125 patients with pHPT (age: 23–83 years); 95 (76%) were female, and 30 (24%) were male. Preoperatively, a standardized medical history including 7 typical symptoms of pHPT was used for routine clinical documentation according to the StuDoQ Thyroid and Parathyroid Registry. **__Results:__** For both groups (mean age: 60.4 years for females and 60.2 years for males), no sex differences were found in serum calcium or parathyroid hormone levels. For females, there was a tendency towards smaller hyperfunctioning parathyroid glands (16.8 vs. 20.5 mm) with less weight (1.14 vs. 1.52 g) and multiglandular disease. Nephrolithiasis was significantly more frequent in men than in women (36.7 vs. 16.8%, respectively; __p__ = 0.036),

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Author

Weber, Theresia; Hillenbrand, Andreas; Peth, Simon; Hummel, Rainer

Publisher

S. Karger AG (ISSN 2297-4725)

Published

2020

Language

EN

Field

Medicine (Health Sciences)