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Can I read Potential Epigenetic Therapeutics for Atherosclerosis Treatment on EtoBox?
Potential Epigenetic Therapeutics for Atherosclerosis Treatment by Ioana Nicorescu; Geesje M. Dallinga; Menno P.J. de Winther; Erik S.G. Stroes; Mahnoush Bahjat is a Medicine article available to read on EtoBox.
What is Potential Epigenetic Therapeutics for Atherosclerosis Treatment about?
Notwithstanding the intense efforts into the understanding and prevention of cardiovascular disease (CVD), its complex pathology remains the leading cause of mortality worldwide. The pivotal role of epigenetic changes in the control of gene expression has been profiled in several diseases, such as cancer and inflammatory disorders. In the last decade, increasing evidence has also linked aberrant epigenetic modulation as a contributor to CVD development. Differential profiles of DNA methylation, histone methylation and acetylation have consistently been observed in tissues and cells (comprising the aortic lesions, vascular endothelium and monocytes) from patients with CVD. This highlights the therapeutic potential of epigenetic drugs for cardiovascular treatment.
Who reads Potential Epigenetic Therapeutics for Atherosclerosis Treatment?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Ioana Nicorescu; Geesje M. Dallinga; Menno P.J. de Winther; Erik S.G. Stroes; Mahnoush Bahjat
- Published
- 2019
- Language
- EN
- Field
- Medicine (Health Sciences)