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This study investigates the hepatoprotective effects of tiliamosine, a bisbenzylisoquinoline alkaloid from Tiliacora racemosa, on non-alcoholic steatohepatitis (NASH) induced by a high-fat diet and diethylnitrosamine in Wistar rats. Tiliamosine significantly reduced lipid accumulation and liver enzyme levels in both in vitro and in vivo models, indicating its potential as a treatment for NASH. The findings suggest that tiliamosine may upregulate hepatic FXR expression while downregulating TNFα expression, p

Author

Anandhi S

Language

EN