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Can I read Cortical Thickness, Gyrification and Sulcal Depth in Trigeminal Neuralgia on EtoBox?

Cortical Thickness, Gyrification and Sulcal Depth in Trigeminal Neuralgia by Li, Meng (author);Yan, Jianhao (author);Wen, Hua (author);Lin, Jinzhi (author);Liang, Lianbao (author);Li, Shumei (author);Xie, Shuangcong (author);Li, Wuming (author);Lin, Chulan (author);Jiang, Guihua (author) is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

What is Cortical Thickness, Gyrification and Sulcal Depth in Trigeminal Neuralgia about?

Neuroimaging studies have documented brain structural alterations induced by chronic pain, particularly in gray matter volume. However, the effects of trigeminal neuralgia (TN), a severe paroxysmal pain disorder, on cortical morphology are not yet known. In this study, we recruited 30 TN patients and 30 age-, and gender-matched healthy controls (HCs). Using Computational Anatomy Toolbox (CAT12), we calculated and compared group differences in cortical thickness, gyrification, and sulcal depth with two-sample t tests (p < 0.05, multiple comparison corrected). Relationships between altered cortical characteristics and pain intensity were investigated with correlation analysis. Compared to HCs, TN patients exhibited significantly decreased cortical thickness in the left inferior frontal, and left medial orbitofrontal cortex; decreased gyrification in the left superior frontal cortex; and decreased sulcal depth in the bilateral superior frontal (extending to anterior cingulate) cortex. In addition, we found significantly negative correlations between the mean cortical thickness in left medial orbitofrontal cortex and pain intensity, and between the mean gyrification in left superior fr

Who reads Cortical Thickness, Gyrification and Sulcal Depth in Trigeminal Neuralgia?

It is typically read by researchers, students, and practitioners in Biochemistry, Genetics and Molecular Biology.

Author
Li, Meng (author);Yan, Jianhao (author);Wen, Hua (author);Lin, Jinzhi (author);Liang, Lianbao (author);Li, Shumei (author);Xie, Shuangcong (author);Li, Wuming (author);Lin, Chulan (author);Jiang, Guihua (author)
Publisher
Springer Science and Business Media LLC
Published
2021
Language
EN
Field
Biochemistry, Genetics and Molecular Biology (Life Sciences)

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