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Effects on functional outcome after IORT-containing multimodality treatment for locally advanced primary and locally recurrent rectal cancer by Guido H.H Mannaerts; Harm J.T Rutten; Hendrik Martijn; Patrick E.J Hanssens; Theo Wiggers is a Medicine article available to read on EtoBox.

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## Purpose: In the treatment of patients with locally advanced primary or locally recurrent rectal cancer, much attention is focused on the oncologic outcome. little is known about the functional outcome. in this study, the functional outcome after a multimodality treatment for locally advanced primary and locally recurrent rectal cancer is analyzed. ## Methods and materials: Between 1994 and 1999, 55 patients with locally advanced primary and 66 patients with locally recurrent rectal cancer were treated with high-dose preoperative external beam irradiation, followed by extended surgery and intraoperative radiotherapy. to assess long-term functional outcome, all patients still alive (n = 97) were asked to complete a questionnaire regarding ongoing morbidity, as well as functional and social impairment. seventy-six of the 79 patients (96%) returned the questionnaire. the median follow-up was 14 months (range: 4-60 months). ## Results: The questionnaire revealed fatigue in 44%, perineal pain in 42%, radiating pain in the leg(s) in 21%, walking difficulties in 36%, and voiding dysfunction in 42% of the patients as symptoms of ongoing morbidity. functional impairment consisted of requi

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Author

Guido H.H Mannaerts; Harm J.T Rutten; Hendrik Martijn; Patrick E.J Hanssens; Theo Wiggers

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2002

Language

EN

Field

Medicine (Health Sciences)