Can I read The Combined Use of Systemic Analgesic/anti-inflammatory Drugs and a Bioactive Topical Desensitizer for Reduced In-office Bleaching Sensitivity Without Jeopardizing the Hydrogen Peroxide Efficacy: a Randomized, Triple Blinded, Split-mouth Clinical Trial on EtoBox?

The Combined Use of Systemic Analgesic/anti-inflammatory Drugs and a Bioactive Topical Desensitizer for Reduced In-office Bleaching Sensitivity Without Jeopardizing the Hydrogen Peroxide Efficacy: a Randomized, Triple Blinded, Split-mouth Clinical Trial by Isabela Dantas Torres de Araújo; Kaiza de Sousa Santos; Thauan Victor Oliveira das Neves Peixoto; Moan Jéfter Fernandes Costa; Isauremi Vieira de Assunção; Boniek Castillo Dutra Borges is a Dentistry article available to read on EtoBox.

What is The Combined Use of Systemic Analgesic/anti-inflammatory Drugs and a Bioactive Topical Desensitizer for Reduced In-office Bleaching Sensitivity Without Jeopardizing the Hydrogen Peroxide Efficacy: a Randomized, Triple Blinded, Split-mouth Clinical Trial about?

## Objective: To evaluate the effect of combined systemic administration of paracetamol 500 mg/codeine phosphate 30 mg (paco) and postoperative topical application of a bioactive desensitizer on in-office bleaching sensitivity and tooth color change. ## Materials and methods: A randomized, triple-blind, split-mouth clinical trial was conducted. forty volunteers ingested paco (n = 20) or placebo (pla) (n = 20). their left/right hemiarches received topical application of a bioactive desensitizer [nano-pTM(np)] and prophylactic paste (pas), generating four treatment approaches: paco/np, paco/pas, pla/np, and pla/pas. two bleaching sessions (35% hydrogen peroxide) were performed, and the pas/np were applied after the procedure. sensitivity was obtained since the first bleaching session up to 7 days post-bleaching. the color change was evaluated using ciede2000 and whiteness index parameters up to 7 days post-bleaching. data were analyzed using one- and two-way anova/tukey post hoc tests (p 0.05). ## Conclusion: The combined approach of systemic administration of paco and postoperative topical application of np reduced the level of in-office bleaching sensitivity without jeopardizing

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Author

Isabela Dantas Torres de Araújo; Kaiza de Sousa Santos; Thauan Victor Oliveira das Neves Peixoto; Moan Jéfter Fernandes Costa; Isauremi Vieira de Assunção; Boniek Castillo Dutra Borges

Publisher

Springer Science and Business Media LLC

Published

2021

Language

EN

Field

Dentistry (Health Sciences)