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## Abstract A small number of epithelial cells which combine features of two cell types were observed in the descending colon and pyloric stomach of the mouse. In the __descending colon__, where the base of the crypts is mainly composed of poorly differentiated “vacuolated” cells, a few of these cells contain, besides the characteristic “vacuoles,” mucous globules identical to those in mucous cells or, less frequently, dense granules such as are found in entero‐endocrine cells. Because there is evidence that the poorly differentiated vacuolated cells give rise to the other cells of the epithelium, those which also contain mucous globules or dense granules are likely to be differentiating into mucous cells or enteroendocrine cells respectively. In the __pyloric stomach__, where the glands are mainly composed of mucous cells, some of which are poorly differentiated, a few of the latter exhibit, besides the mucous globules, entero‐endocrine type granules or features of caveolated cells. It is likely that the poorly differentiated mucous cells give rise to the other gland cells; and, therefore, those mucus‐containing cells which also display dense granules or caveolated cell features a

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Author

A. Nabeyama

Publisher

Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0002-9106)

Published

1975

Language

EN

Field

Medicine (Health Sciences)