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What is GI Bleeding Risk with Direct Oral Anticoagulants about?

This document discusses prevention of gastrointestinal bleeding in patients taking direct oral anticoagulants (DOACs). It outlines that certain patient characteristics like age over 65, renal or liver dysfunction, low body weight, and use of other medications can increase the risk of GI bleeding in those taking DOACs. It reviews the pharmacology of different types of DOACs and how their absorption and elimination can be affected by interactions with P-glycoprotein or CYP enzymes. It also discusses potential

Author

fitra annisa

Language

EN