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Fasting serum adiponectin concentration is reduced in Indo‐Asian subjects and is related to HDL cholesterol by G. Valsamakis; R. Chetty; P. G. McTernan; N. M. Al‐Daghri; A. H. Barnett; S. Kumar is a Medicine article available to read on EtoBox.
What is Fasting serum adiponectin concentration is reduced in Indo‐Asian subjects and is related to HDL cholesterol about?
**Aims:** Adiponectin is a 30‐kDa protein secreted by adipose tissue. The aim of the present study was to compare serum adiponectin in male Indo‐Asian and Caucasian subjects and examine its association with fat topography and metabolic parameters. **Methods:** Diabetic and non‐diabetic male subjects (n = 48) were studied. A single observer carried out blood pressure and anthropometric measurements. Serum glucose, insulin, lipid profile and adiponectin (measured by RIA) were measured on a fasting sample. **Results:** There was no statistically significant difference in serum adiponectin between diabetic and BMI‐matched non‐diabetic subjects. However, serum adiponectin was lower in Indo‐Asians compared with BMI‐matched Caucasians, [median adiponectin (interquartile range) 3.3 (2.1–3.9) vs. 4.9 (3.5–6.6) μg/ml respectively (p = 0.016)]. Univariate analysis showed serum adiponectin to be positively associated with HDL in diabetic (p = 0.039) and non‐diabetic subjects (p = 0.0098). Waist circumference (p = 0.02), saggital diameter (p = 0.04) were negatively correlated with serum adiponectin in diabetic subjects. Multiple regression analysis including waist, HDL, fasting insulin, age, di
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- Author
- G. Valsamakis; R. Chetty; P. G. McTernan; N. M. Al‐Daghri; A. H. Barnett; S. Kumar
- Publisher
- John Wiley and Sons; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley; Research Square (ISSN 1462-8902)
- Published
- 2003
- Language
- EN
- Field
- Medicine (Health Sciences)