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From Porcine To Synthetic Overcoming Translational Hurdles in Exosome-Mediated Ocular Drug Delivery by Subhadra Rout is a document available to read on EtoBox.

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This document discusses the challenges of delivering therapeutics to the posterior segments of the eye due to biological barriers and presents a novel approach using porcine-derived extracellular vesicles (SEVs) to bypass these barriers for treating retinoblastoma. However, the reliance on animal-derived materials poses immunological and scalability issues, prompting the proposal of a synthetic alternative using Solid Lipid Nanoparticles (SLNs) functionalized with human EGF and Folic Acid. The paper outline

Author
Subhadra Rout
Language
EN