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This review discusses the role of heterogeneous macrophage lineages in heart valve development and disease, highlighting the presence of both resident and recruited macrophages in the aortic and mitral valves. It emphasizes the recruitment of monocyte-derived macrophages during myxomatous heart valve disease and their contribution to valve degeneration. The document also explores the clinical significance and potential therapeutic applications of targeting these macrophage populations in cardiovascular dise

Author

yuanliu99

Language

EN