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Isolation and characterization of UHMWPE wear particles down to ten nanometers in size from in vitro hip and knee joint simulators by J.L. Tipper; A.L. Galvin; S. Williams; H.M.J. McEwen; M.H. Stone; E. Ingham; J. Fisher is a Engineering article available to read on EtoBox.
What is Isolation and characterization of UHMWPE wear particles down to ten nanometers in size from in vitro hip and knee joint simulators about?
## Abstract There is currently considerable interest in the wear debris and osteolytic potential of different types of bearings used in total joint replacements. The biological activity of the wear debris is dependent on the size and volume of the particles produced. Wear volume also plays an important role in the functional biological activity of a joint replacement. __In vitro__ studies have shown that crosslinking of ultra high molecular weight polyethylene (UHMWPE) acetabular cups and tibial trays produces a reduction in wear volume, and crosslinking has now been introduced clinically for both types of prostheses. Previous studies have identified both micron and submicron‐sized polyethylene wear particles. The aim of this study was to characterize the wear and wear particles generated from moderately crosslinked GUR 1020 GVF UHMWPE acetabular cups and tibial trays in hip and knee joint wear simulators down to 10 nanometers in size. The wear rates of the two prosthesis types were very similar at 25.6 ± 5.3 mm^3^ per million cycles for the hip prostheses and 22.75 ± 5.95 mm^3^ per million cycles for the knee prostheses. Nanometer‐sized wear particles were isolated and characteriz
Who reads Isolation and characterization of UHMWPE wear particles down to ten nanometers in size from in vitro hip and knee joint simulators?
It is typically read by researchers, students, and practitioners in Engineering.
- Author
- J.L. Tipper; A.L. Galvin; S. Williams; H.M.J. McEwen; M.H. Stone; E. Ingham; J. Fisher
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 1549-3296)
- Published
- 2006
- Language
- EN
- Field
- Engineering (Physical Sciences)