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Can I read Quercetin Alleviates Gliotoxin-induced Duckling Tissue Injury by Inhibiting Oxidative Stress, Inflammation and Increasing Heterophil Extracellular Traps Release on EtoBox?
Quercetin Alleviates Gliotoxin-induced Duckling Tissue Injury by Inhibiting Oxidative Stress, Inflammation and Increasing Heterophil Extracellular Traps Release by Qinqin Jin; Meiyi Chen; Zha Jin; Yuqian Jiang; Hongrong Hong; Yuxiao Qian; Wei Liu; Xinxin Gao; Liqiang Jiang; Jingnan Xu; Quan Liu; Zhengkai Wei is a Medicine article available to read on EtoBox.
What is Quercetin Alleviates Gliotoxin-induced Duckling Tissue Injury by Inhibiting Oxidative Stress, Inflammation and Increasing Heterophil Extracellular Traps Release about?
Aspergillus fumigatus causes aspergillosis with high morbidity and mortality in the duck industry. As a vital virulence factor produced by A. fumigatus, gliotoxin (GT) is widely present in food and feed, threatening duck industry and human health. Quercetin is a polyphenol flavonoid compound from natural plants with anti-inflammatory and antioxidant functions. However, the effects of quercetin on ducklings with GT poisoning are unknown. The model of ducklings with GT poisoning was established, and the protective effects and molecular mechanisms of quercetin on ducklings with GT poisoning were investigated. Ducklings were divided into control, GT, and quercetin groups. A model of GT (2.5 mg/kg) poisoning in ducklings was successfully established. Quercetin protected GT-induced liver and kidney functions and alleviated GT-induced alveolar wall thickening in lungs, cell fragmentation, and inflammatory cell infiltration in liver and kidney. Quercetin decreased malondialdehyde (MDA) and increased superoxide dismutase (SOD) and catalase (CAT) after GT treatment. Quercetin significantly reduced GT-induced mRNA expression levels of inflammatory factors. Furthermore, quercetin increased GT-
Who reads Quercetin Alleviates Gliotoxin-induced Duckling Tissue Injury by Inhibiting Oxidative Stress, Inflammation and Increasing Heterophil Extracellular Traps Release?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Qinqin Jin; Meiyi Chen; Zha Jin; Yuqian Jiang; Hongrong Hong; Yuxiao Qian; Wei Liu; Xinxin Gao; Liqiang Jiang; Jingnan Xu; Quan Liu; Zhengkai Wei
- Publisher
- Elsevier BV
- Published
- 2023
- Language
- EN
- Field
- Medicine (Life Sciences)