Can I read Enteroviruses and Idiopathic Dilated Cardiomyopathy on EtoBox?

Enteroviruses and Idiopathic Dilated Cardiomyopathy by Dr Hugh R. Cochrane; Felicity E. B. May; Thomas Ashcroft; John H. Dark is a Medicine article available to read on EtoBox.

What is Enteroviruses and Idiopathic Dilated Cardiomyopathy about?

Previous studies have suggested that some cases of idiopathic dilated cardiomyopathy (IDC) are due to persistent viral infection following an episode of viral myocarditis. Viral RNA sequences have recently been detected in material from patients with IDC using molecular biological techniques. We tested 40 samples from recipients' hearts explanted at cardiac transplantation for the presence of enteroviral RNA sequences, using a Northern blotting technique. Material from 19 cases of IDC and 21 cases of non-cardiomyopathic cardiac failure was examined together with Coxsackie-virus-infected neonatal mouse heart as a positive control and non-infected adult mouse heart as a negative control. A sharp band of viral RNA was detected in the positive control sample. No hybridization signal attributable to viral RNA was obtained for the negative control or for any of the test samples. We conclude that the role of enteroviruses in the pathogenesis of cardiomyopathy is not fully established and that further study is warranted.

Who reads Enteroviruses and Idiopathic Dilated Cardiomyopathy?

Author

Dr Hugh R. Cochrane; Felicity E. B. May; Thomas Ashcroft; John H. Dark

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0022-3417)

Published

1991

Language

EN

Field

Medicine (Health Sciences)