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Can I read Deregulated expression of the TAL1 gene by t(1;5)(p32;q31) in patient with T-cell acute lymphoblastic leukemia on EtoBox?
Deregulated expression of the TAL1 gene by t(1;5)(p32;q31) in patient with T-cell acute lymphoblastic leukemia by Sylvie François; Eric Delabesse; Laurence Baranger; Marie Dautel; Charles Foussard; Marc Boasson; Odile Blanchet; Olivier Bernard; Elizabeth A. Macintyre; Norbert Ifrah is a Medicine article available to read on EtoBox.
What is Deregulated expression of the TAL1 gene by t(1;5)(p32;q31) in patient with T-cell acute lymphoblastic leukemia about?
TAL1 gene deregulation is frequent in T-cell acute lymphoblastic leukemia (T-ALL) and can result from translocations involving 1p32 or, more frequently, from a cytogenetically undetectable interstitial deletion of chromosome 1. This study presents a case of T-ALL with a t(1;5)(p32;q31) involving TAL1, in which the breakpoint occurs approximately 10 kbp 5' to the gene and leads to transcriptional activation and synthesis of a TAL1 protein, and extends the spectrum of recognized TAL1 gene translocations associated with T-ALL.
Who reads Deregulated expression of the TAL1 gene by t(1;5)(p32;q31) in patient with T-cell acute lymphoblastic leukemia?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Sylvie François; Eric Delabesse; Laurence Baranger; Marie Dautel; Charles Foussard; Marc Boasson; Odile Blanchet; Olivier Bernard; Elizabeth A. Macintyre; Norbert Ifrah
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); Wiley-Liss Inc; Wiley (ISSN 1045-2257)
- Published
- 1998
- Language
- EN
- Field
- Medicine (Life Sciences)