Can I read Role of D-mannose in urinary tract infections – a narrative review on EtoBox?
Role of D-mannose in urinary tract infections – a narrative review by Ala-Jaakkola, Reeta (author);Laitila, Arja (author);Ouwehand, Arthur C. (author);Lehtoranta, Liisa (author) is a Medicine article available to read on EtoBox.
What is Role of D-mannose in urinary tract infections – a narrative review about?
## Abstract Urinary tract infections (UTIs) are one of the most prevalent bacterial diseases worldwide. Despite the efficacy of antibiotics targeted against UTI, the recurrence rates remain significant among the patients. Furthermore, the development of antibiotic resistance is a major concern and creates a demand for alternative treatment options. D-mannose, a monosaccharide naturally found in fruits, is commonly marketed as a dietary supplement for reducing the risk for UTIs. Research suggests that supplemented D-mannose could be a promising alternative or complementary remedy especially as a prophylaxis for recurrent UTIs. When excreted in urine, D-mannose potentially inhibits Escherichia coli, the main causative organism of UTIs, from attaching to urothelium and causing infection. In this review, we provide an overview of UTIs, E. coli pathogenesis and D-mannose and outline the existing clinical evidence of D-mannose in reducing the risk of UTI and its recurrence. Furthermore, we discuss the potential effect mechanisms of D-mannose against uropathogenic E.coli.
Who reads Role of D-mannose in urinary tract infections – a narrative review?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Ala-Jaakkola, Reeta (author);Laitila, Arja (author);Ouwehand, Arthur C. (author);Lehtoranta, Liisa (author)
- Publisher
- Springer Science and Business Media LLC
- Published
- 2022
- Language
- EN
- Field
- Medicine (Health Sciences)