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Interstitial Brachytherapy for Salvage Treatment of Vaginal Recurrences in Previously Unirradiated Endometrial Cancer Patients by Subir Nag; Sherif Yacoub; Larry J Copeland; Jeffery M Fowler is a Medicine article available to read on EtoBox.

What is Interstitial Brachytherapy for Salvage Treatment of Vaginal Recurrences in Previously Unirradiated Endometrial Cancer Patients about?

## Purpose: To evaluate whether interstitial brachytherapy can effectively salvage vaginal recurrence from endometrial carcinoma. ## Methods and materials: Between september 1989 and september 2000, 13 previously unirradiated patients (mean age 70 years) with isolated vaginal recurrences from endometrial adenocarcinoma were treated with interstitial low-dose-rate brachytherapy with or without additional external beam radiotherapy. brachytherapy was delivered using a modified perineal syed template loaded with (192)ir. the central cylinder was loaded with high-activity (192)ir (n = 12) or (137)cs (n = 1). ## Results: The patients had initially presented with figo stage i (n = 11) or iii (n = 2) cancer. vaginal recurrences were diagnosed at a mean interval of 27.5 months after hysterectomy (range 2-83). the patients were followed for a median of 60 months (range 15-105). ten patients had recurrence at the vaginal apex and three had recurrence in the lower two-thirds of the vagina. the median time to recurrence was 22 months. the tumor size ranged from 1.5 to 6 cm (mean 2.2, median 2.5). eleven of 13 patients received 45-50-gy pelvic external beam radiotherapy, followed by a mean inte

Who reads Interstitial Brachytherapy for Salvage Treatment of Vaginal Recurrences in Previously Unirradiated Endometrial Cancer Patients?

Author

Subir Nag; Sherif Yacoub; Larry J Copeland; Jeffery M Fowler

Publisher

Elsevier Science; Elsevier ; Elsevier BV (ISSN 0360-3016)

Published

2002

Language

EN

Field

Medicine (Health Sciences)