Opening book details…
Can I read Comparison of Adequacy Between Transbronchial Lung Cryobiopsy Samples and Endobronchial Ultrasound‐guided Transbronchial Needle Aspiration Samples for Next‐generation Sequencing Analysis on EtoBox?
Comparison of Adequacy Between Transbronchial Lung Cryobiopsy Samples and Endobronchial Ultrasound‐guided Transbronchial Needle Aspiration Samples for Next‐generation Sequencing Analysis by Mari Tone; Minoru Inomata; Nobuyasu Awano; Naoyuki Kuse; Kohei Takada; Jonsu Minami; Yutaka Muto; Kazushi Fujimoto; Toshio Kumasaka; Takehiro Izumo is a Medicine article available to read on EtoBox.
What is Comparison of Adequacy Between Transbronchial Lung Cryobiopsy Samples and Endobronchial Ultrasound‐guided Transbronchial Needle Aspiration Samples for Next‐generation Sequencing Analysis about?
## Background: Most lung cancer patients present with lesions in both lung fields and lymphadenopathy. thus, transbronchial lung cryobiopsy (tblc) and endobronchial ultrasound-guided transbronchial needle aspiration (ebus-tbna) are commonly performed for diagnosing lung cancer. however, the adequacy of these samples for next-generation sequencing (ngs) analysis remains unclear. this study aimed to compare the adequacy between tblc and ebus-tbna samples for ngs analysis. ## Methods: This retrospective cohort study included patients whose lung samples were collected via tblc or ebus-tbna and analyzed using ngs. out of 46 genes, the number of genes in tbna and tblc samples that could not be assessed via ngs analysis was mainly evaluated. ## Results: A total of 37 patients were included and classified into two groups (tblc group, n = 18 and tbna group, n = 19). the mean number of genes that could not be evaluated via ngs analysis was significantly lower in the tblc group than in the tbna group (0.9 vs. 10.3, p = 0.024). the median total area of tumor cells in tblc samples was significantly greater than that in tbna samples (6.3 [1.6-4.2] vs. 2.6 [0.2-17.3] mm , p < 0.01). in the tbna g
Who reads Comparison of Adequacy Between Transbronchial Lung Cryobiopsy Samples and Endobronchial Ultrasound‐guided Transbronchial Needle Aspiration Samples for Next‐generation Sequencing Analysis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Mari Tone; Minoru Inomata; Nobuyasu Awano; Naoyuki Kuse; Kohei Takada; Jonsu Minami; Yutaka Muto; Kazushi Fujimoto; Toshio Kumasaka; Takehiro Izumo
- Publisher
- Wiley (Blackwell Publishing); Blackwell Publishing Asia Pty Ltd; Wiley (ISSN 1759-7706)
- Published
- 2020
- Language
- EN
- Field
- Medicine (Health Sciences)