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Can I read Collagen nerve protector in rat sciatic nerve repair: A morphometric and histological analysis on EtoBox?
Collagen nerve protector in rat sciatic nerve repair: A morphometric and histological analysis by Paul D. Kim; Austin Hayes; Faiq Amin; Yelena Akelina; Arthur P. Hays; Melvin P. Rosenwasser is a Medicine article available to read on EtoBox.
What is Collagen nerve protector in rat sciatic nerve repair: A morphometric and histological analysis about?
## Abstract Peripheral nerve repair is often complicated by fibroblastic scar formation, nerve dysfunction, and traumatic neuroma formation. Use of bio‐absorbable protective wraps may improve outcomes of these repairs. This study histologically compared the incidence of neuroma formation, connective tissue proliferation, and axonal regrowth in transected rat sciatic nerves repaired with and without tubular collagen nerve sleeves. Twenty Sprague‐Dawley rats underwent unilateral sharp sciatic nerve transection and microscopic nerve repair with four epineural sutures and were randomly treated with or without an encircling collagen nerve sleeve. Normal nerves from the contralateral sciatic nerve were also examined. At sacrifice three months later, the nerves were evaluated for traumatic neuroma formation, perineural scar formation, and morphometric analysis. Histological examination of normal and repaired nerves by a neuropathologist demonstrated healing, minimal Wallerian degeneration and no traumatic neuroma formation. Distal section analysis (nine nonwrapped, 10 wrapped), revealed no significant differences in total fascicular area, myelinated fibers per nerve, fiber density, myelin
Who reads Collagen nerve protector in rat sciatic nerve repair: A morphometric and histological analysis?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Paul D. Kim; Austin Hayes; Faiq Amin; Yelena Akelina; Arthur P. Hays; Melvin P. Rosenwasser
- Publisher
- John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0738-1085)
- Published
- 2010
- Language
- EN
- Field
- Medicine (Health Sciences)