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The THIN study evaluated the neuroprotective effects of therapeutic hypothermia induced by phase changing material on MRI biomarkers in infants with hypoxic-ischaemic encephalopathy (HIE) in India. Results showed that cooled infants had significantly higher fractional anisotropy in the posterior limb of the internal capsule and fewer severe MRI abnormalities compared to non-cooled infants. The study supports the implementation of therapeutic hypothermia in resource-limited settings, highlighting its potenti
- Author
- Abhishek Sg
- Language
- EN