Can I read Break-Induced Replication and Genome Instability on EtoBox?

Break-Induced Replication and Genome Instability by retro9ankit is a document available to read on EtoBox.

What is Break-Induced Replication and Genome Instability about?

The document discusses break-induced replication (BIR), a mechanism for repairing double-strand DNA breaks that have only one repairable end. BIR plays a role in repairing breaks from collapsed replication forks or eroded telomeres, but can also be a source of genetic instability through mutations, loss of heterozygosity, and chromosomal rearrangements. Microhomology-mediated BIR can generate copy number variations and complex rearrangements potentially linked to human disease.

Author

retro9ankit

Language

EN