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Can I read Inter- and Intra-individual Variations in Normal Urinary Glycine Betaine Excretion on EtoBox?
Inter- and Intra-individual Variations in Normal Urinary Glycine Betaine Excretion by Michael Lever; Wendy Atkinson; Peter C.B. Sizeland; Stephen T. Chambers; Peter M. George is a Medicine article available to read on EtoBox.
What is Inter- and Intra-individual Variations in Normal Urinary Glycine Betaine Excretion about?
## Objectives: To establish whether normal human subjects excrete glycine betaine at a constant rate. ## Design and methods: Urine was collected from ten normal healthy male subjects for 14 days, during which fluid intake was systematically varied from 3 l per day. glycine betaine, sorbitol and creatinine excretions were estimated per day and as millimole per mol creatinine. ## Results: The intrasubject sd of urine glycine betaine was 3.5 mmol/mol creatinine, and the intersubject sd 5.8 mmol/mol creatinine. the intrasubject sd of plasma glycine betaine was 10.2 mol/l and the intersubject sd 14.2 mol/l. water load had little effect on glycine betaine excretion and plasma glycine betaine. after 12 years, excretions and plasma concentrations tended to parallel the initial results. ## Conclusions: Normal subjects have consistent individual glycine betaine excretions that are not strongly influenced by urine volume. abnormal excretions, or significant changes in excretion, can be interpreted as indicating a pathological process.
Who reads Inter- and Intra-individual Variations in Normal Urinary Glycine Betaine Excretion?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- Michael Lever; Wendy Atkinson; Peter C.B. Sizeland; Stephen T. Chambers; Peter M. George
- Publisher
- Elsevier Science; Elsevier ; Elsevier BV (ISSN 0009-9120)
- Published
- 2007
- Language
- EN
- Field
- Medicine (Health Sciences)