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Tetanus Pathogenesis and Mechanisms by Karun Bhattarai is a document available to read on EtoBox.
What is Tetanus Pathogenesis and Mechanisms about?
Tetanus occurs when spores of Clostridium tetani enter damaged human tissue and produce tetanus toxin. The toxin travels up motor neurons to the spinal cord and brainstem, where it blocks neurotransmitter release from inhibitory interneurons. This results in increased muscle tone and painful spasms due to a loss of inhibition of motor neurons. Tetanus toxin effects are long-lasting and require new nerve growth to recover. The toxin is produced as an inactive polypeptide and activated after release to bind t
- Author
- Karun Bhattarai
- Language
- EN