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Network Module Extraction with Positive and Negative Co-regulation by T. A. Rahman; D. K. Bhattacharyya is a scholarly article available to read on EtoBox.

What is Network Module Extraction with Positive and Negative Co-regulation about?

This paper presents a method, referred here as TDNME, to find topk strongly correlated modules from a gene Co-expression Network (CEN). The proposed TDNME initially mines a gene expression dataset for finding both positively and negatively strongly corregulated gene pairs, which become the seeds for the formation of strongly correlated network modules in the next phase. We have tested our method on four publicly available benchmark microarray datasets and the modules have been biologically validated in terms of both Q value and p value.

Author

T. A. Rahman; D. K. Bhattacharyya

Publisher

ACM

Published

2012

Language

EN