Opening book details…
Can I read ^13^C‐methacetin breath test for monitoring hepatic function in cirrhotic patients before and after liver transplantation on EtoBox?
^13^C‐methacetin breath test for monitoring hepatic function in cirrhotic patients before and after liver transplantation by A. Petrolati; D. Festi; G. De Berardinis; L. Colaiocco‐Ferrante; D. Di Paolo; G. Tisone; M. Angelico is a Medicine article available to read on EtoBox.
What is ^13^C‐methacetin breath test for monitoring hepatic function in cirrhotic patients before and after liver transplantation about?
## Summary **Background** : In patients with chronic liver disease, the measurement of liver function is critical for monitoring disease progression, predicting the prognosis and choosing therapeutic strategies. The ^13^C‐methacetin breath test is a simple, non‐invasive diagnostic tool based on an inexpensive, non‐toxic substance, which allows the accurate measurement of liver functional reserve. **Aim** : To investigate the ^13^C‐methacetin breath test as a tool to monitor hepatic function in liver transplant candidates and recipients. **Methods** : Twenty‐eight cirrhotic patients listed for orthotopic liver transplantation and 10 healthy controls were studied. The ^13^C‐methacetin breath test (75 mg __per os__) was performed at baseline and at 12‐week intervals. Intra‐operative measurements were obtained during the liver transplantation procedure in nine patients. Results were expressed as the ^13^C‐methacetin cumulative oxidation percentage 45 min after substrate ingestion. **Results** : The mean ^13^C‐methacetin cumulative oxidation at 45 min was 16.4 ± 3.5% in healthy controls and 5.4 ± 4.2% in cirrhotic patients at the time of listing. In 11 patients who underwent successful
Who reads ^13^C‐methacetin breath test for monitoring hepatic function in cirrhotic patients before and after liver transplantation?
It is typically read by researchers, students, and practitioners in Medicine.
- Author
- A. Petrolati; D. Festi; G. De Berardinis; L. Colaiocco‐Ferrante; D. Di Paolo; G. Tisone; M. Angelico
- Publisher
- John Wiley and Sons; Blackwell Publishing; Wiley (Blackwell Publishing); Blackwell Publishing Inc.; Wiley; Research Square (ISSN 0269-2813)
- Published
- 2003
- Language
- EN
- Field
- Medicine (Health Sciences)