Can I read An α2-Macroglobulinlike Activity in the Blood of Chelicerate and Mandibulate Arthropods on EtoBox?

An α2-Macroglobulinlike Activity in the Blood of Chelicerate and Mandibulate Arthropods by Dr. Peter B. Armstrong; Michael T. Rossner; James P. Quigley is a Environmental Science article available to read on EtoBox.

What is An α2-Macroglobulinlike Activity in the Blood of Chelicerate and Mandibulate Arthropods about?

The az-macroglobulins are large molecular weight proteinasebinding proteins that inhibit the ability of proteinases to hydrolyze protein substrates without suppressing activity against amide or ester substrates. They are also able to protect the active site of bound proteinases from active site inhibitors of suitably high molecular weight. The ability to protect the amidolytic activity of trypsin from the macromolecular active site inhibitor, soybean trypsin inhibitor, was used to demonstrate an az-macroglobulinlike activity in the blood of the horseshoe crab, Limulus polyphemus and the crustaceans Libinia emarginata (the spider crab) and Cancer borealis (the Jonah crab). The az-macroglobulinlike activities of L. polyphemus and L. emarginata are sensitive to methylamine, but that of C. borealis is relatively insensitive. The molecular weights (mw) of the trypsin-protecting proteins in L. ernarginata and C. borealis, estimated from gelfiltration studies, are, respectively, 480 x lo3 and 460 x lo3, and are significantly smaller than that of L. polyphemus (Mr = 570 x lo3).

Who reads An α2-Macroglobulinlike Activity in the Blood of Chelicerate and Mandibulate Arthropods?

Author

Dr. Peter B. Armstrong; Michael T. Rossner; James P. Quigley

Publisher

John Wiley and Sons; Wiley (John Wiley & Sons); John Wiley & Sons Inc.; Wiley (ISSN 0022-104X)

Published

1985

Language

EN

Field

Environmental Science (Life Sciences)