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Microvascular Damage Evaluation Based on Nailfold Videocapillarosopy in Sarcoidosis by Şerife Şeyda Zengin Acemoğlu; İpek Türk; Mehmet Ali Aşık; Ayşegül Özdoğan Bircan; Pelin Pınar Deniz; Didem Arslan; İsmail Hanta; İlker Ünal is a Medicine article available to read on EtoBox.

What is Microvascular Damage Evaluation Based on Nailfold Videocapillarosopy in Sarcoidosis about?

Objectives Microvascular damage is thought to play a role in the pathogenesis of sarcoidosis. We aimed to evaluate the nailfold capillaroscopy (NVC) pattern to detect microvascular changes in patients with sarcoidosis and the relationship of capillaroscopic parameters with clinical variables and disease-related measurements. Patients and methods Forty-two patients with sarcoidosis and 42 age-and sex-matched patients with systemic sclerosis (SSc) and healthy individuals were included in this cross-sectional case-control study. Patients aged 18-80 years who met the current American Thoracic Society criteria for sarcoidosis were included. NVC was performed by a digital microscope under a magnification of × 200. Capillary density, number of dilated, giant and neoangiogenic capillaries, capillary loop diameter, capillary shape, micro-hemorrhages, and number of avascular areas, were evaluated by an assessor who was blind to the groups allocation. Results Among the capillaroscopic parameters, neoangiogenesis and dilated capillaries, which can be seen in the pattern of scleroderma, were detected in patients with sarcoidosis but not significantly different from the control group (p = 0.055;

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Author

Şerife Şeyda Zengin Acemoğlu; İpek Türk; Mehmet Ali Aşık; Ayşegül Özdoğan Bircan; Pelin Pınar Deniz; Didem Arslan; İsmail Hanta; İlker Ünal

Publisher

Springer Science and Business Media LLC

Published

2023

Language

EN

Field

Medicine (Health Sciences)