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Can I read COVID-19 during Pregnancy and Postpartum:: I) Pathobiology of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) at Maternal-Fetal Interface on EtoBox?

COVID-19 during Pregnancy and Postpartum:: I) Pathobiology of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) at Maternal-Fetal Interface by Sreus A. G. Naidu; Roger A. Clemens; Peter Pressman; Mehreen Zaigham; Kamran Kadkhoda; Kelvin J. A. Davies; A. Satyanarayan Naidu is a Medicine article available to read on EtoBox.

What is COVID-19 during Pregnancy and Postpartum:: I) Pathobiology of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) at Maternal-Fetal Interface about?

Coronavirus Disease 2019 (COVID-19) triggered by (SARS-CoV-2) infection has been declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Oxidative stress and its related metabolic syndromes are potential risk factors in the susceptibility to, and severity of COVID-19. In concert with the earliest reports of COVID-19, obstetricians started to diagnose and treat SARS-CoV-2 infections during pregnancy ("COVID-19-"). High metabolic demand to sustain normal fetal development increases the burden of oxidative stress in pregnancy. Intracellular redox changes intertwined with acute phase responses at the maternal-fetal interface could amplify during pregnancy. Interestingly, mother-to-fetus transmission of SARS-CoV-2 has not been detected in most of the COVID-19- cases. This relative absence of vertical transmission may be related to the presence of lactoferrin in the placenta, amniotic fluid, and lacteal secretions. However, the cytokine-storm induced during COVID-19- may cause severe inflammatory damage to the fetus, and if uncontrolled, may later result in autism spectrum-like disorders and brain development abnormalities in neonates. Considering this serious healt

Who reads COVID-19 during Pregnancy and Postpartum:: I) Pathobiology of Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) at Maternal-Fetal Interface?

It is typically read by researchers, students, and practitioners in Medicine.

Author
Sreus A. G. Naidu; Roger A. Clemens; Peter Pressman; Mehreen Zaigham; Kamran Kadkhoda; Kelvin J. A. Davies; A. Satyanarayan Naidu
Publisher
Informa plc; Informa UK (Taylor & Francis); Informa Healthcare; Informa UK Limited (ISSN 1939-0211)
Published
2020
Language
EN
Field
Medicine (Health Sciences)

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