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Breast Cancers Are Immunogenic: Immunologic Analyses and a Phase II Pilot Clinical Trial Using Mutation-Reactive Autologous Lymphocytes by Nikolaos Zacharakis, Lutfi M. Huq, Samantha J. Seitter, Sanghyun P. Kim, Jared J. Gartner, Sivasish Sindiri, Victoria K. Hill, Yong F. Li, Biman C. Paria, Satyajit Ray, Billel Gasmi, Chyi-chia Lee, Todd D. Prickett, Maria R. Parkhurst, Paul F. Robbins, Michelle M. Langhan, Thomas E. Shelton, Anup Y. Parikh, Shoshana T. Levi, Jonathan M. Hernandez, Chuong D. Hoang, Richard M. Sherry, James C. Yang, Steven A. Feldman, Stephanie L. Goff, and Steven A. Rosenberg is a book available to read on EtoBox.

What is Breast Cancers Are Immunogenic: Immunologic Analyses and a Phase II Pilot Clinical Trial Using Mutation-Reactive Autologous Lymphocytes about?

Breast Cancers Are Immunogenic: Immunologic Analyses and a Phase II Pilot Clinical Trial Using Mutation-Reactive Autologous ... 1 INTRODUCTION 1 PATIENTS AND METHODS 2 Eligibility 2 Study Design and Treatment 2 End Points 2 Statistical Considerations 2 RESULTS 3 Study Group 3 Isolation of TIL From Tumor Fragments 3 Identification of Somatic Mutations in Resected Metastatic Deposits 3 Screening for Identification of Immunogenic Mutations 3 Neoantigen Characteristics 3 Adoptive Transfer of Selected Neoantigen-Specific TIL With Pembrolizumab 6 DISCUSSION 11 REFERENCES 14 jcojcoJCOJournal of Clinical Oncology0732-183XWolters Kluwer HealthJCO.21.0217010.1200/JCO.21.02170Original ReportsTranslat ... 15 JCO 0.0:JCO.21.02170

Author

Nikolaos Zacharakis, Lutfi M. Huq, Samantha J. Seitter, Sanghyun P. Kim, Jared J. Gartner, Sivasish Sindiri, Victoria K. Hill, Yong F. Li, Biman C. Paria, Satyajit Ray, Billel Gasmi, Chyi-chia Lee, Todd D. Prickett, Maria R. Parkhurst, Paul F. Robbins, Michelle M. Langhan, Thomas E. Shelton, Anup Y. Parikh, Shoshana T. Levi, Jonathan M. Hernandez, Chuong D. Hoang, Richard M. Sherry, James C. Yang, Steven A. Feldman, Stephanie L. Goff, and Steven A. Rosenberg

Language

EN