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Syntheses of Sugar-related Trihydroxyazepanes from Simple Carbohydrates and Their Activities as Reversible Glycosidase Inhibitors by Søren M Andersen; Christian Ekhart; Inge Lundt; Arnold E Stütz is a Biochemistry, Genetics and Molecular Biology article available to read on EtoBox.

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Five diastereomeric trideoxy-1,6-iminohexitols were synthesised, and their inhibitory activities were determined against selected glycosidases. For comparison, 1,4,5-trideoxy-1,5-imino-D-lyxo-hexitol, the 4-deoxy derivative of 1-deoxymannojirimicin, was prepared by enzymatic isomerisation of 6-azido-3,6-dideoxy-D-ribo-hexose into the corresponding 2-ulose and subsequent hydrogenation accompanied by intramolecular reductive amination.

Who reads Syntheses of Sugar-related Trihydroxyazepanes from Simple Carbohydrates and Their Activities as Reversible Glycosidase Inhibitors?

Author

Søren M Andersen; Christian Ekhart; Inge Lundt; Arnold E Stütz

Publisher

Elsevier Science; Elsevier ; Elsevier Ltd.; Elsevier BV (ISSN 0008-6215)

Published

2000

Language

EN

Field

Biochemistry, Genetics and Molecular Biology (Life Sciences)